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UGT2B10

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UGT2B10
Identifikatori
AlijasiUGT2B10
Spoljašnji IDOMIM: 600070 MGI: 2140962 HomoloGene: 117389 GeneCards: UGT2B10
Obrazac RNK izražavanja
More reference expression data
Ortolozi
VrsteČovekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001290091
NM_001075
NM_001144767

NM_153598

RefSeq (protein)

NP_001066
NP_001138239
NP_001277020

n/a

Location (UCSC)n/aChr 5: 87.04 – 87.05 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

UDP-glukuronoziltransferaza 2B10 je enzim koji je kod ljudi kodiran genom UGT2B10.[4][5] On je odgovoran za glukuronidaciju nikotina i kotinina.[6][7]

  1. ^ а б в GRCm38: Ensembl release 89: ENSMUSG00000029260 - Ensembl, May 2017
  2. ^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  3. ^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Jin CJ, Miners JO, Lillywhite KJ, Mackenzie PI (јул 1993). „cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily”. Biochemical and Biophysical Research Communications. 194 (1): 496—503. PMID 8333863. doi:10.1006/bbrc.1993.1847. 
  5. ^ „Entrez Gene: UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10”. 
  6. ^ Chen G, Giambrone NE, Dluzen DF, Muscat JE, Berg A, Gallagher CJ, Lazarus P (октобар 2010). „Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms”. Cancer Research. 70 (19): 7543—52. PMC 2998997Слободан приступ. PMID 20876810. doi:10.1158/0008-5472.CAN-09-4582. 
  7. ^ Wassenaar CA, Conti DV, Das S, Chen P, Cook EH, Ratain MJ, et al. (јануар 2015). „UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers”. Cancer Epidemiology, Biomarkers & Prevention. 24 (1): 94—104. PMC 4294984Слободан приступ. PMID 25277794. doi:10.1158/1055-9965.EPI-14-0804.