Undekaprenil-difosfooligosaharid—protein glikotransferaza
| Undekaprenil-difosfooligosaharid—protein glikotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.99.19 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Undekaprenil-difosfooligosaharid—protein glikotransferaza (EC 2.4.99.19, PglB) je enzim sa sistematskim imenom tritrans,heptacis-undekaprenil-difosfooligosaharid:protein-L-asparagin N-beta-D-oligosaharidotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- tritrans,heptacis-undekaprenil difosfooligosaharid + [protein]-L-asparagin tritrans,heptacis-undekaprenil difosfat + glikoprotein sa oligosaharidnim lancom vezanim N-beta-D-glikozilnom vezom za protein L-asparagin
Ovaj bakterijski enzim je izolovan iz Campylobacter jejuni i Campylobacter lari.
Reference
[уреди | уреди извор]- ^ Maita, N., Nyirenda, J., Igura, M., Kamishikiryo, J. and Kohda, D. (2010). „Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases”. J. Biol. Chem. 285: 4941—4950. PMID 20007322.
- ^ Lizak, C., Gerber, S., Numao, S., Aebi, M. and Locher, K.P. (2011). „X-ray structure of a bacterial oligosaccharyltransferase”. Nature. 474: 350—355. PMID 21677752.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Undecaprenyl-diphosphooligosaccharide---protein+glycotransferase на US National Library of Medicine Medical Subject Headings (MeSH)
