15-Cis-fitoen desaturaza
| 15-Cis-fitoen desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.5.5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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15-Cis-fitoen desaturaza (EC 1.3.5.5, fitoenska desaturaza (nespecifična), PDS) je enzim sa sistematskim imenom 15-cis-fitoen:plastohinon oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 15-cis-fitoen + 2 plastohinon 9,15,9'-tricis-zeta-karoten + 2 plastohinol (sveukupna reakcija)
(1a) 15-cis-fitoen + plastohinon 15,9'-dicis-fitofluen + plastohinol (1b) 15,9'-dicis-fitofluen + plastohinon 9,15,9'-tricis-zeta-karoten + plastohinol
This enzim is involved in biosintezu karotenoida kod biljki i cijanobakterija. Enzim iz Synechococcus can takođe koristi NAD+ i NADP+ kao elektronske akceptore pod anaerobnim uslovima. Enzim iz Gentiana lutea nije aktivan na NAD+ i NADP+.
Reference[уреди | уреди извор]
- ^ Breitenbach, J., Zhu, C. and Sandmann, G. (2001). „Bleaching herbicide norflurazon inhibits phytoene desaturase by competition with the cofactors”. J. Agric. Food Chem. 49: 5270—5272. PMID 11714315.
- ^ Schneider, C., Boger, P. and Sandmann, G. (1997). „Phytoene desaturase: heterologous expression in an active state, purification, and biochemical properties”. Protein Expr. Purif. 10: 175—179. PMID 9226712.
- ^ Fraser, P.D., Linden, H. and Sandmann, G. (1993). „Purification and reactivation of recombinant Synechococcus phytoene desaturase from an overexpressing strain of Escherichia coli”. Biochem. J. 291: 687—692. PMID 8489496.
- ^ Breitenbach, J. & Sandmann, G. (2005). „ζ-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene”. Planta. 220: 785—793. PMID 15503129.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 15-cis-phytoene+desaturase на US National Library of Medicine Medical Subject Headings (MeSH)
