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Saharoza sintaza

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Saharoza sintaza
Identifikatori
EC broj2.4.1.13
CAS broj2604301
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Saharoza sintaza (EC 2.4.1.13, UDPglukoza-fruktoza glukoziltransferaza, saharozna sintetaza, saharoza-UDP glukoziltransferaza, saharoza-uridin difosfatna glukoziltransferaza, uridin difosfoglukoza-fruktozna glukoziltransferaza) je enzim sa sistematskim imenom NDP-glukoza:D-fruktoza 2-alfa-D-glukoziltransferaza.[1][2][3][4][5][6][7][8][9][10] Ovaj enzim katalizuje sledeću hemijsku reakciju

NDP-glukoza + D-fruktoza NDP + saharoza

Mada se UDP generalno smatra preferentnim nukleozid difosfatom za sintezu saharoze, brojne studije su pokazale da ADP isto tako može da bude efektivan akceptor.

  1. ^ Avigad, G. & Milner, Y. (1966). „UDP-glucose:fructose transglucosylase from sugar beet roots”. Methods Enzymol. 8: 341—345. 
  2. ^ Cardini, C.E., Leloir, L.F. and Chiriboga, J. (1955). „The biosynthesis of sucrose”. J. Biol. Chem. 214: 149—155. PMID 14367373. 
  3. ^ Delmer, D.P. (1972). „The purification and properties of sucrose synthetase from etiolated Phaseolus aureus' seedlings”. J. Biol. Chem. 247: 3822—3828. PMID 4624446. 
  4. ^ Murata, T., Sugiyama, T., Minamikawa, T. and Akazawa, T. (1966). „Enzymic mechanism of starch synthesis in ripening rice grains. Mechanism of the sucrose-starch conversion”. Arch. Biochem. Biophys. 113: 34—44. PMID 5941994. 
  5. ^ Nakai, T., Konishi, T., Zhang, X.-Q., Chollet, R., Tonouchi, N., Tsuchida, T., Yoshinaga, F., Mori, H., Sakai, F. and Hayashi, T. (1998). „An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11”. Plant Cell Physiol. 39: 1337—1341. PMID 10050318. 
  6. ^ Porchia, A.C., Curatti, L. and Salerno, G.L. (1999). „Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence”. Planta. 210: 34—40. PMID 10592030. 
  7. ^ Ross, H.A. & Davies, H.V. (1992). „Purification and characterization of sucrose synthase from the cotyledons of Vicia fava L”. Plant Physiol. 100: 1008—1013. PMID 16653008. 
  8. ^ Silvius, J.E. & Snyder, F.W. (1979). „Comparative enzymic studies of sucrose metabolism in the taproots and fibrous roots of Beta vulgaris L”. Plant Physiol. 64: 1070—1073. PMID 16661094. 
  9. ^ Tanase, K. & Yamaki, S. (2000). „Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit”. Plant Cell Physiol. 41: 408—414. PMID 10845453. 
  10. ^ Baroja-Fernández, E., Muñnoz, F.J., Saikusa, T., Rodríguez-López, M., Akazawa, T. and Pozueta-Romero, J. (2003). „Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants”. Plant Cell Physiol. 44: 500—509. PMID 12773636. 

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