11b-hidroksisteroid dehidrogenaza
| 11b-hidroksisteroid dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 11-beta-hydroxysteroid dehydrogenase dimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.1.1.146 | ||||||||
| CAS broj | 9041-46-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
11b-hidroksisteroid dehidrogenaza (EC 1.1.1.146, kortikosteroid 11beta-dehidrogenaza, beta-hidroksisteroidna dehidrogenaza, 11beta-hidroksi steroidna dehidrogenaza, kortikosteroidna 11-reduktaza, dehidrogenaza, 11beta-hidroksi steroid) je enzim sa sistematskim imenom 11beta-hidroksisteroid:NADP+ 11-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 11beta-hidroksisteroid + NADP+ 11-oksosteroid + NADPH + H+
Reference[уреди | уреди извор]
- ^ Agarwal, A.K., Monder, C., Eckstein, B. and White, P.C. (1989). „Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase”. J. Biol. Chem. 264: 18939—18943. PMID 2808402.
- ^ Bush, I.E., Hunter, S.A. and Meigs, R.A. (1968). „Metabolism of 11-oxygenated steroids. Metabolism in vitro by preparations of liver”. Biochem. J. 107: 239—258. PMID 4384445.
- ^ Lakshmi, V. & Monder, C. (1988). „Purification and characterization of the corticosteroid 11β-dehydrogenase component of the rat liver 11β-hydroxysteroid dehydrogenase complex”. Endocrinology. 123: 2390—2398. PMID 3139396.
- ^ Phillips, D.M., Lakshmi, V. and Monder, C. (1989). „Corticosteroid 11β-dehydrogenase in rat testis”. Endocrinology. 125: 209—216. PMID 2661206.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 11beta-hydroxysteroid+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
