Heksobarbital

Из Википедије, слободне енциклопедије
Heksobarbital
(IUPAC) ime
5-(cikloheks-1-en-1-il)-1,5-dimetil-1,3-diazinan-2,4,6-trion
Klinički podaci
Robne marke Barbidorm, Citopan, Cyclopal, Cyclopan
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 56-29-1
ATC kod N05CA16 , N01AF02
DrugBank DB01355
KEGG[1] C11723 YesY
ChEMBL[2] CHEMBL5706 YesY
Hemijski podaci
Formula C12H16N2O3 
Mol. masa 236.267
SMILES eMolekuli & PubHem
Fizički podaci
Tačka topljenja 146.5 °C (296 °F)
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status
Način primene Oralno

Heksobarbital je barbiturat koji je efektivan kao hipnotik i sedativ.[3][4][5][6][7][8]

Reference[уреди]

  1. ^ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG“. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  2. ^ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery“. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  3. ^ Takenoshita R, Toki S: [New aspects of hexobarbital metabolism: stereoselective metabolism, new metabolic pathway via GSH conjugation, and 3-hydroxyhexobarbital dehydrogenases] Yakugaku Zasshi. 2004 Dec;124(12):857-71. PMID 15577260
  4. ^ Wahlstrom G: A study of the duration of acute tolerance induced with hexobarbital in male rats. Pharmacol Biochem Behav. 1998 Apr;59(4):945-8. PMID 9586853
  5. ^ Korkmaz S, Ljungblad E, Wahlstrom G: Interaction between flumazenil and the anesthetic effects of hexobarbital in the rat. Brain Res. 1995 Apr 10;676(2):371-7. PMID 7614008
  6. ^ Dall V, Orntoft U, Schmidt A, Nordholm L: Interaction of the competitive AMPA receptor antagonist NBQX with hexobarbital. Pharmacol Biochem Behav. 1993 Sep;46(1):73-6. PMID 8255925
  7. ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs“. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682. 
  8. ^ Nucleic Acids Res (2008). DrugBank: a knowledgebase for drugs, drug actions and drug targets. 36. pp. D901-6. PMID 18048412. 

Spoljašnje veze[уреди]


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