Receptor glukagonu sličnog peptida 2
| Receptor glukagonu sličnog peptida 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simbol | GLP2R | ||||||||||
| Vanjski ID | OMIM: 603659 MGI: 2136733 HomoloGene: 3132 IUPHAR: GLP-2 GeneCards: GLP2R Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 9340 | 93896 | |||||||||
| Ensembl | ENSG00000065325 | ENSMUSG00000049928 | |||||||||
| UniProt | O95838 | Q5IXF8 | |||||||||
| RefSeq (mRNA) | NM_004246.1 | NM_175681.3 | |||||||||
| RefSeq (protein) | NP_004237.1 | NP_783612.2 | |||||||||
| Lokacija (UCSC) |
Chr 17: 9.73 - 9.8 Mb |
Chr 11: 67.48 - 67.58 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Gen za receptor glukagonu sličnog peptida 2 (GLP-2) se nalazi na hromozomu 17.[1]
Reference[уреди | уреди извор]
- ^ Brubaker PL, Drucker DJ (2002). „Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors” (PDF). Recept. Channels. 8 (3–4): 179—88. PMID 12529935. doi:10.1080/10606820213687. Архивирано из оригинала (PDF) 20. 10. 2006. г. Приступљено 24. 08. 2007.
Literatura[уреди | уреди извор]
- Burrin DG, Petersen Y, Stoll B, Sangild P (2001). „Glucagon-like peptide 2: a nutrient-responsive gut growth factor”. J. Nutr. 131 (3): 709—12. PMID 11238747.
- Munroe DG; Gupta AK; Kooshesh F; et al. (1999). „Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2”. Proc. Natl. Acad. Sci. U.S.A. 96 (4): 1569—73. PMC 15520
. PMID 9990065. doi:10.1073/pnas.96.4.1569. - Yusta B; Huang L; Munroe D; et al. (2000). „Enteroendocrine localization of GLP-2 receptor expression in humans and rodents”. Gastroenterology. 119 (3): 744—55. PMID 10982769. doi:10.1053/gast.2000.16489.
- Thulesen J; Knudsen LB; Hartmann B; et al. (2002). „The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist”. Regul. Pept. 103 (1): 9—15. PMID 11738243. doi:10.1016/S0167-0115(01)00316-0.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Koehler JA, Yusta B, Drucker DJ (2005). „The HeLa cell glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways”. Mol. Endocrinol. 19 (2): 459—73. PMID 15471943. doi:10.1210/me.2004-0196.
- Ørskov C; Hartmann B; Poulsen SS; et al. (2005). „GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors”. Regul. Pept. 124 (1–3): 105—12. PMID 15544847. doi:10.1016/j.regpep.2004.07.009.
- Mahon MJ, Shimada M (2005). „Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors”. FEBS Lett. 579 (3): 803—7. PMID 15670850. doi:10.1016/j.febslet.2004.12.056.
- Estall JL, Koehler JA, Yusta B, Drucker DJ (2005). „The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation”. J. Biol. Chem. 280 (23): 22124—34. PMID 15817468. doi:10.1074/jbc.M500078200.
- Guan X; Karpen HE; Stephens J; et al. (2006). „GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow”. Gastroenterology. 130 (1): 150—64. PMID 16401478. doi:10.1053/j.gastro.2005.11.005.
- Sams A, Hastrup S, Andersen M, Thim L (2006). „Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines”. Eur. J. Pharmacol. 532 (1–2): 18—23. PMID 16448646. doi:10.1016/j.ejphar.2005.12.001.
Vidi još[уреди | уреди извор]
Spoljašnje veze[уреди | уреди извор]
- „Glucagon Receptor Family: GLP-2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 16. 02. 2015. г.
- glucagon-like+peptide+receptor на US National Library of Medicine Medical Subject Headings (MeSH)