Ketamolol

Ketamolol
Nazivi
	IUPAC naziv 2-[2-[3-(tert-Butilamino)-2-hidroksipropoksi]fenoksi]-N-metilacetamid
Identifikacija
CAS broj	34919-98-7 ; 77590-95-5 (hidrohlorid) ;
3D model (Jmol)	interaktivna slika;
ChemSpider	48483;
KEGG	D03449;
PubChem C ID	53698;
UNII	Z0VD1633O8 ; 5UNK5C6QM5 (hidrohlorid) ;
	SMILES CC(C)(C)NCC(COC1=CC=CC=C1OCC(=O)NC)O; ; ; ; ; ;
Svojstva
Hemijska formula	C16H26N2O4
Molarna masa	310,39 g·mol−1
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	Reference infokutije

Ketamolol je beta adrenergički antagonist, specifičnije β₁-adrenergični blokator.^[4]

Sinteza[уреди | уреди извор]

^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Klausner, MA; Irwin, C; Mullane, JF; Shand, DG; Leese, PT; Arnold, JD; Wollberg, W; Wagner, NB; Wagner, GS (1988). „Effect of cetamolol on epinephrine-induced hypokalemia”. Journal of Clinical Pharmacology. 28 (8): 751—6. PMID 2905711. S2CID 30767741. doi:10.1002/j.1552-4604.1988.tb03210.x.
^ GB 1458392, "Optically-active 1-aryloxy-2,3-epoxypropane derviatives", published 1976-12-15, assigned to Imperial Chemical Industries Ltd.
^ BE 767781, "Alkanolamines", published 1971-11-29, assigned to Imperial Chemical Industries Ltd.
^ D. J. Lecount, C. J. Squire, U.S. Patent 4.059.622 (1977 to ICI).