CP 47,497
 | |
| IUPAC ime | |
|---|---|
2-[(1R,3S)-3-hidroksicikloheksil]- 5-(2-metiloktan-2-il)fenol | |
| Pravni status | |
| Pravni status |
|
| Identifikatori | |
| CAS broj | 70434-82-1  70434-92-3 (C8 homolog) |
| ATC kod | none |
| PubChem | CID 125835 |
| ChEMBL | CHEMBL163701 |
| Hemijski podaci | |
| Formula | C21H34O2 |
| Molarna masa | 318,492 g/mol |
| |
CP 47,497 ili (C7)-CP 47,497 je agonist kanabinoidnog receptora, koji je razvilo preduzeće Pfizer tokom 1980-tih.[1] Ovaj materijal ima analgetsko dejstvo i koristi se u naučnim istraživanjima. Ono je potentan CB1 agonist sa Kd vrednošću od 2,1 nM.[2][3][4]
Vidi još
[uredi | uredi izvor]Reference
[uredi | uredi izvor]- ^ Weissman A, Milne GM, Melvin LS Jr. Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol. Journal of Pharmacology and Experimental Therapeutics. 1982 Nov;223(2):516-23. PMID 6290642
- ^ Shim JY, Welsh WJ, Howlett AC. Homology model of the CB1 cannabinoid receptor: sites critical for nonclassical cannabinoid agonist interaction. Biopolymers. 2003;71(2):169-89. PMID 12767117
- ^ Roger Pertwee. Cannabinoids. Handbook of Experimental Pharmacology Volume 168. Springer. ISBN 978-3-540-22565-2.
- ^ Little PJ, et al. Pharmacology and stereoselectivity of structurally novel cannabinoids in mice. Journal of Pharmacology and Experimental Therapeutics 1988; 247:1046–1051.
