С Википедије, слободне енциклопедије
Metoklopramid Prodajno ime Apo-Metoclop, Cerucal, Clopra, Clopra-Yellow Drugs.com Monografija Način primene Intramaskularno, intravenozno, oralno Poluvreme eliminacije 5-6 h Izlučivanje Renalno, 85%
CAS broj 364-62-5 Y ATC kod A03FA01 (WHO PubChem CID 4168 IUPHAR/BPS 241 DrugBank DB01233 Y ChemSpider 4024 Y KEGG C07868 Y ChEBI CHEBI:107736 Y ChEMBL CHEMBL86 Y Formula C 14 H 22 Cl N 3 O 2 Molarna masa 299,796
CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC
InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
Y Key:TTWJBBZEZQICBI-UHFFFAOYSA-N
Y
Tačka topljenja
Metoklopramid je organsko jedinjenje , koje sadrži 14 atoma ugljenika i ima molekulsku masu od 299,796 Da .[1] [2] [3] [4]
^ JUSTIN-BESANCON L, LAVILLE C: [ANTIEMETIC ACTION OF METOCLOPRAMIDE WITH RESPECT TO APOMORPHINE AND HYDERGINE.] C R Seances Soc Biol Fil. 1964;158:723-7. PMID 14186927
^ Tonini M, Candura SM, Messori E, Rizzi CA: Therapeutic potential of drugs with mixed 5-HT4 agonist/5-HT3 antagonist action in the control of emesis. Pharmacol Res. 1995 May;31(5):257-60. PMID 7479521
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs” . Nucleic Acids Res . 39 (Database issue): D1035—41. PMC 3013709 PMID 21059682 . doi :10.1093/nar/gkq1126 . ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets” . Nucleic acids research . 36 (Database issue): D901—6. PMC 2238889 PMID 18048412 . doi :10.1093/nar/gkm958 . ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods” . J. Phys. Chem. A . 102 : 3762—3772. doi :10.1021/jp980230o . ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices” . Chem Inf. Comput. Sci . 41 : 1488—1493. PMID 11749573 . doi :10.1021/ci000392t . ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties” . J. Med. Chem . 43 : 3714—3717. PMID 11020286 . doi :10.1021/jm000942e .
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. PMID 21059682. doi:10.1093/nar/gkq1126.
