С Википедије, слободне енциклопедије
Prometazin Prodajno ime Allergan, Aprobit, Avomine, Dimapp Drugs.com Monografija Način primene Topikalno, intramaskularno, intravenozno, oralno Poluvreme eliminacije 16-19 h Izlučivanje Renalno
CAS broj 60-87-7 Y ATC kod D04AA10 (WHO ), R06 AD05 PubChem CID 4927 DrugBank DB01069 Y ChemSpider 4758 Y KEGG C07404 Y ChEBI CHEBI:8461 Y ChEMBL CHEMBL643 Y Formula C 17 H 20 N 2 S Molarna masa 284,419
CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Y Key:PWWVAXIEGOYWEE-UHFFFAOYSA-N
Y
Tačka topljenja 60 °C (140 °F)Tačka ključanja 190 °C (374 °F)
Prometazin je organsko jedinjenje , koje sadrži 17 atoma ugljenika i ima molekulsku masu od 284,419 Da .[1] [2] [3]
^ Peters RJ Jr, Kelder SH, Markham CM, Yacoubian GS Jr, Peters LA, Ellis A: Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) onset and perceived addiction among urban Houstonian adolescents: an addiction trend in the city of lean. J Drug Educ. 2003;33(4):415-25. PMID 15237866
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs” . Nucleic Acids Res . 39 (Database issue): D1035—41. PMC 3013709 . PMID 21059682 . doi :10.1093/nar/gkq1126 .
^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets” . Nucleic acids research . 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412 . doi :10.1093/nar/gkm958 .
^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods” . J. Phys. Chem. A . 102 : 3762—3772. doi :10.1021/jp980230o .
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices” . Chem Inf. Comput. Sci . 41 : 1488—1493. PMID 11749573 . doi :10.1021/ci000392t .
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties” . J. Med. Chem . 43 : 3714—3717. PMID 11020286 . doi :10.1021/jm000942e .
Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja) .