Jošinori Osumi

Jošinori Osumi
Osumi (2016)
Lični podaci
Datum rođenja	(1945-02-09)9. februar 1945.
Mesto rođenja	Fukuoka, Japansko carstvo
Obrazovanje	Univerzitet u Tokiju
Naučni rad
Polje	ćelijski biolog
Institucija	Tokijski institut za tehnologiju
Poznat po	autofagije
Nagrade	Nobelova nagrada za fiziologiju ili medicinu (2016)
Zvanični veb-sajt
www.ohsumilab.aro.iri.titech.ac.jp/english.htmlwww.ohsumilab.aro.iri.titech.ac.jp/english.html

Jošinori Osumi (jap. 大隅 良典; Fukuoka, 9. februar 1945) japanski je ćelijski biolog koji je specijalizovan za autofagiju. Autofagija je proces koji ćelije koriste da bi razgradile i reciklirale ćelijske komponente. Osumi je profesor na Tokijskom institutu za tehnologiju. Dobio je nagradu Kjoto za bazne nauke 2012. godine i Nobelovu nagradu za fiziologiju ili medicinu 2016. godine za otkrića mehanizama autofagije.

Dela

Njegovi originalni nazali o autofagiji ćelija kvasca:

• Ohsumi, Yoshinori; et al. (oktobar 1992). „Autophagy in Yeast Demonstrated with Proteinase-Deficient Mutants and Conditions for Its Induction”. The Journal of Cell Biology. 119 (2): 301—311. 
• Ohsumi, Yoshinori; et al. (mart 1994). „Ultrastructural Analysis of the Autophagic Process in Yeast: Detection of Autophagosomes and Their Characterization”. The Journal of Cell Biology. 124 (6): 903—913. 

Drugo:

• Tsukada, M; Ohsumi, Y (25. 10. 1993). „Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.”. FEBS letters. 333 (1-2): 169—74. PMID 8224160. 
• Mizushima, N; Noda, T; Yoshimori, T; Tanaka, Y; Ishii, T; George, MD; Klionsky, DJ; Ohsumi, M; Ohsumi, Y (24. 9. 1998). „A protein conjugation system essential for autophagy.”. Nature. 395 (6700): 395—8. PMID 9759731. 
• Kabeya, Y.; Mizushima, N.; Ueno, T.; Yamamoto, A.; Kirisako, T.; Noda, T.; Kominami, E.; Ohsumi, Y.; Yoshimori, T. (2000). „LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing”. The EMBO Journal. 19 (21): 5720—5728. PMC 305793 . PMID 11060023. doi:10.1093/emboj/19.21.5720. 
• Ichimura, Y; Kirisako, T; Takao, T; Satomi, Y; Shimonishi, Y; Ishihara, N; Mizushima, N; Tanida, I; Kominami, E; Ohsumi, M; Noda, T; Ohsumi, Y (23. 11. 2000). „A ubiquitin-like system mediates protein lipidation.”. Nature. 408 (6811): 488—92. PMID 11100732. 
• Ohsumi, Y (mart 2001). „Molecular dissection of autophagy: two ubiquitin-like systems.”. Nature reviews. Molecular cell biology. 2 (3): 211—6. PMID 11265251. 
• Kuma, A; Hatano, M; Matsui, M; Yamamoto, A; Nakaya, H; Yoshimori, T; Ohsumi, Y; Tokuhisa, T; Mizushima, N (23. 12. 2004). „The role of autophagy during the early neonatal starvation period.”. Nature. 432 (7020): 1032—6. PMID 15525940. 
• Hanada, T; Noda, NN; Satomi, Y; Ichimura, Y; Fujioka, Y; Takao, T; Inagaki, F; Ohsumi, Y (28. 12. 2007). „The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.”. The Journal of biological chemistry. 282 (52): 37298—302. PMID 17986448. 
• Ohsumi, Yoshinori; et al. (decembar 2013). „Highly Oxidized Peroxisomes Are Selectively Degraded via Autophagy in Arabidopsis”. The Plant Cell. American Society of Plant Biologists (ASPB). 25 (12): 4967—4983. 
• Yamamoto, H; Ohsumi, Y (6. 10. 2015). „The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy.”. The Journal of Biological Chemistry. 290: 29506—29518. doi:10.1074/jbc.M115.684233. 
• Yamamoto, H; Ohsumi, Y (11. 7. 2016). „The intrinsically disordered protein Atg13 mediates supramolecular assembly of autophagy initiation complexes.”. Dev. Cell. 38 (1): 86—99. PMID 27404361. 

Spoljašnje veze

• Academic profile on a Japanese website Arhivirano na sajtu Wayback Machine (5. jun 2020)
• Curriculum vitae on his homesite
• An official press release announcing Ohsumi will receive the 2016 Nobel Prize in Physiology or Medicine
• Yoshinori Ohsumi of Japan Wins Nobel Prize for Study of ‘Self-Eating’ Cells