С Википедије, слободне енциклопедије
Felbamat |
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| Prodajno ime | Felbamyl, Felbatol, Taloxa |
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| Drugs.com | Monografija |
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| Način primene | Oralno |
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| Poluvreme eliminacije | 20-23 h |
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| CAS broj | 25451-15-4  Y |
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| ATC kod | N03AX10 (WHO) |
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| PubChem | CID 3331 |
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| DrugBank | DB00949 Y |
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| ChemSpider | 3214 Y |
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| KEGG | C07501 Y |
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| ChEBI | CHEBI:4995 Y |
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| ChEMBL | CHEMBL1094 Y |
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| Formula | C11H14N2O4 |
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| Molarna masa | 238,240 |
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NC(=O)OCC(COC(N)=O)C1=CC=CC=C1
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InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15) YKey:WKGXYQFOCVYPAC-UHFFFAOYSA-N Y
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| Tačka topljenja | 1.515 °C (2.759 °F) |
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Felbamat je organsko jedinjenje, koje sadrži 11 atoma ugljenika i ima molekulsku masu od 238,240 Da.[1][2][3]
- ^ Leppik IE, Dreifuss FE, Pledger GW, Graves NM, Santilli N, Drury I, Tsay JY, Jacobs MP, Bertram E, Cereghino JJ, et al.: Felbamate for partial seizures: results of a controlled clinical trial. Neurology. 1991 Nov;41(11):1785-9. PMID 1944909
- ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709
. PMID 21059682. doi:10.1093/nar/gkq1126. уреди
- ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958. уреди
- ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
- ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t. уреди
- ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e. уреди
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