С Википедије, слободне енциклопедије
Nifluminska kiselina Prodajno ime Actol, Flogovital, Forenol, Landruma Drugs.com acid.html Monografija Poluvreme eliminacije 2,5 h
CAS broj 4394-00-7 Y ATC kod M02AA17 (WHO M01 AX02 PubChem CID 4488 IUPHAR/BPS 2439 DrugBank DB04552 Y ChemSpider 4333 Y KEGG C13698 Y Formula C 13 H 9 F 3 N 2 O 2 Molarna masa 282,218
OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
InChI=1S/C13H9F3N2O2/c14-13(15,16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20)
Y Key:JZFPYUNJRRFVQU-UHFFFAOYSA-N
Y
Tačka topljenja
Nifluminska kiselina je organsko jedinjenje , koje sadrži 13 atoma ugljenika i ima molekulsku masu od 282,218 Da .[1] [2] [3]
^ Criddle DN, de Moura RS, Greenwood IA, Large WA: Inhibitory action of niflumic acid on noradrenaline- and 5-hydroxytryptamine-induced pressor responses in the isolated mesenteric vascular bed of the rat. Br J Pharmacol. 1997 Mar;120(5):813-8. PMID 9138686
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs” . Nucleic Acids Res . 39 (Database issue): D1035—41. PMC 3013709 PMID 21059682 . doi :10.1093/nar/gkq1126 . ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets” . Nucleic acids research . 36 (Database issue): D901—6. PMC 2238889 PMID 18048412 . doi :10.1093/nar/gkm958 . ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods” . J. Phys. Chem. A . 102 : 3762—3772. doi :10.1021/jp980230o . ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices” . Chem Inf. Comput. Sci . 41 : 1488—1493. PMID 11749573 . doi :10.1021/ci000392t . ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties” . J. Med. Chem . 43 : 3714—3717. PMID 11020286 . doi :10.1021/jm000942e .
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. PMID 21059682. doi:10.1093/nar/gkq1126.
