GPR1
| G protein-spregnuti receptor 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | GPR1; | ||||||||||
| Vanjski ID | OMIM: 600239 MGI: 2385324 HomoloGene: 21094 IUPHAR: GPR1 GeneCards: GPR1 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 2825 | 241070 | |||||||||
| Ensembl | ENSG00000183671 | ENSMUSG00000046856 | |||||||||
| UniProt | P46091 | Q8K087 | |||||||||
| RefSeq (mRNA) | NM_005279 | NM_146250 | |||||||||
| RefSeq (protein) | NP_005270 | NP_666362 | |||||||||
| Lokacija (UCSC) |
Chr 2: 206.75 - 206.79 Mb |
Chr 1: 63.12 - 63.15 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR1, G protein-spregnuti receptor 1', je protein koji je kod čoveka kodiran GPR1 genom.[1][2]
GPR1 deluje kao receptor za hemerin.[3] Osim ovog receptora hemerin aktivira CMKLR1 i CCRL2.
Literatura
[уреди | уреди извор]- ^ „Entrez Gene: GPR1 G protein-coupled receptor 1”.
- ^ Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF (1994). . „Cloning of human genes encoding novel G protein-coupled receptors”. Genomics. 23 (3): 609—18. PMID 7851889. doi:10.1006/geno.1994.1549.
- ^ Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ (2008). . „The genetic design of signaling cascades to record receptor activation”. Proc. Natl. Acad. Sci. U.S.A.. 105 (1): 64—9. PMC 2224232
. PMID 18165312. doi:10.1073/pnas.0710487105.
Dodatna literatura
[уреди | уреди извор]- Shimizu N; Soda Y; Kanbe K; et al. (1999). . „An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cells.”. J. Virol.. 73 (6): 5231—9. PMC 112576 . PMID 10233994.
- Tokizawa S; Shimizu N; Hui-Yu L; et al. (2000). . „Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor.”. Kidney Int.. 58 (2): 607—17. PMID 10916084. doi:10.1046/j.1523-1755.2000.00207.x.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). . „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Kang MK; Kameta A; Shin KH; et al. (2003). . „Senescence-associated genes in normal human oral keratinocytes.”. Exp. Cell Res.. 287 (2): 272—81. PMID 12837283. doi:10.1016/S0014-4827(03)00061-2.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). . „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Hillier LW; Graves TA; Fulton RS; et al. (2005). . „Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”. Nature. 434 (7034): 724—31. PMID 15815621. doi:10.1038/nature03466.
- Jinno-Oue A; Shimizu N; Soda Y; et al. (2005). . „The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1.”. J. Biol. Chem.. 280 (35): 30924—34. PMID 15919664. doi:10.1074/jbc.M500195200.
- Otsuki T; Ota T; Nishikawa T; et al. (2007). . „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”. DNA Res.. 12 (2): 117—26. PMID 16303743. doi:10.1093/dnares/12.2.117.
- Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). . „Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.”. Genome Res.. 16 (1): 55—65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406.
