Receptor slobodnih masnih kiselina 3
| Receptor slobodnih masnih kiselina 3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | FFAR3; FFA3R; GPR41 | ||||||||||
| Vanjski ID | OMIM: 603821 MGI: 2685324 HomoloGene: 82482 IUPHAR: FFA3 GeneCards: FFAR3 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 2865 | 233080 | |||||||||
| Ensembl | ENSG00000185897 | ENSMUSG00000019429 | |||||||||
| UniProt | O14843 | Q3UFD7 | |||||||||
| RefSeq (mRNA) | NM_005304.3 | NM_001033316.2 | |||||||||
| RefSeq (protein) | NP_005295.1 | NP_001028488.1 | |||||||||
| Lokacija (UCSC) |
Chr 19: 35.85 - 35.85 Mb |
Chr 7: 31.64 - 31.64 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Receptor slobodnih masnih kiselina 3 (FFA3) je G protein spregnuti receptor koji je kod ljudi kodiran FFAR3 genom.[1][2]
Reference[уреди | уреди извор]
- ^ „Entrez Gene: FFAR3 free fatty acid receptor 3”.
- ^ Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'Dowd BF (1997). „A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1”. Biochem. Biophys. Res. Commun. 239 (2): 543—7. PMID 9344866. doi:10.1006/bbrc.1997.7513.
Literatura[уреди | уреди извор]
- Brown AJ, Jupe S, Briscoe CP (2005). „A family of fatty acid binding receptors.”. DNA Cell Biol. 24 (1): 54—61. PMID 15684720. doi:10.1089/dna.2005.24.54.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Brown AJ; Goldsworthy SM; Barnes AA; et al. (2003). „The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.”. J. Biol. Chem. 278 (13): 11312—9. PMID 12496283. doi:10.1074/jbc.M211609200.
- Le Poul E; Loison C; Struyf S; et al. (2003). „Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.”. J. Biol. Chem. 278 (28): 25481—9. PMID 12711604. doi:10.1074/jbc.M301403200.
- Xiong Y; Miyamoto N; Shibata K; et al. (2004). „Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.”. Proc. Natl. Acad. Sci. U.S.A. 101 (4): 1045—50. PMC 327148 . PMID 14722361. doi:10.1073/pnas.2637002100.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Yonezawa T, Kobayashi Y, Obara Y (2007). „Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.”. Cell. Signal. 19 (1): 185—93. PMID 16887331. doi:10.1016/j.cellsig.2006.06.004.
