S1PR5

Sfingozin 1-fosfatni receptor 5
Identifikatori
Simboli	S1PR5; EDG8; Edg-8; S1P5; SPPR-1; SPPR-2
Vanjski ID	OMIM: 605146 MGI: 2150641 HomoloGene: 11031 IUPHAR: S1P5 GeneCards: S1PR5 Gene
Ontologija gena Molekularna funkcija • aktivnost G-protein spregnutog receptora • aktivnost faktora guanil-nukleotidne razmene • vezivanje masne kiseline Celularna komponenta • ćelijska membrana • integralno sa ćelijskom membranom Biološki proces • metabolički proces energetske rezerve • signalni put G-protein spregnutog receptora
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta	Čovek	Miš
Entrez	53637	94226
Ensembl	ENSG00000180739	ENSMUSG00000045087
UniProt	Q9H228	Q91X56
RefSeq (mRNA)	NM_001166215.1	NM_053190.2
RefSeq (protein)	NP_001159687.1	NP_444420.1
Lokacija (UCSC)	Chr 19: 10.62 - 10.63 Mb	Chr 9: 21.05 - 21.05 Mb
PubMed pretraga	[1]	[2]

Sfingozin 1-fosfat receptor 5 (S1PR5) je ljudski gen koji kodira G protein spregnuti receptor za koji se vezuje lipidni signalni molekul sfingozin 1-fosfat (S1P).

Vidi još

• Lizofosfolipidni receptor

Literatura

• Im DS; Heise CE; Ancellin N; et al. (2000). „Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.”. J. Biol. Chem. 275 (19): 14281—6. PMID 10799507. doi:10.1074/jbc.275.19.14281. 
• Malek RL; Toman RE; Edsall LC; et al. (2001). „Nrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptors.”. J. Biol. Chem. 276 (8): 5692—9. PMID 11069896. doi:10.1074/jbc.M003964200. 
• Hla T (2001). „Sphingosine 1-phosphate receptors.”. 64 (1-4): 135—142. PMID 11331101. 
• Im DS, Clemens J, Macdonald TL, Lynch KR (2001). „Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors.”. Biochemistry. 40 (46): 14053—60. PMID 11705398. doi:10.1021/bi011606i. 
• Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1-3): 97—101. PMID 12044878. doi:10.1016/S0014-5793(02)02775-8. 
• Niedernberg A, Scherer CR, Busch AE, Kostenis E (2002). „Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists.”. Biochem. Pharmacol. 64 (8): 1243—50. PMID 12234605. doi:10.1016/S0006-2952(02)01289-3. 
• Kothapalli R, Kusmartseva I, Loughran TP (2003). „Characterization of a human sphingosine-1-phosphate receptor gene (S1P5) and its differential expression in LGL leukemia.”. Biochim. Biophys. Acta. 1579 (2-3): 117—23. PMID 12427546. doi:10.1016/S0167-4781(02)00529-8. 
• Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899. 
• Vogler R; Sauer B; Kim DS; et al. (2003). „Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing.”. J. Invest. Dermatol. 120 (4): 693—700. PMID 12648236. doi:10.1046/j.1523-1747.2003.12096.x. 
• Ota T; Suzuki Y; Nishikawa T; et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40—5. PMID 14702039. doi:10.1038/ng1285. 
• Grimwood J; Gordon LA; Olsen A; et al. (2004). „The DNA sequence and biology of human chromosome 19.”. Nature. 428 (6982): 529—35. PMID 15057824. doi:10.1038/nature02399. 
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
• Ulfig N, Briese M (2005). „Evidence for the presence of the sphingosine-1-phosphate receptor Edg-8 in human radial glial fibers.”. Acta Histochem. 106 (5): 373—8. PMID 15530552. doi:10.1016/j.acthis.2004.08.002. 
• Rual JF; Venkatesan K; Hao T; et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network.”. Nature. 437 (7062): 1173—8. PMID 16189514. doi:10.1038/nature04209. 
• Otsuki T; Ota T; Nishikawa T; et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”. DNA Res. 12 (2): 117—26. PMID 16303743. doi:10.1093/dnares/12.2.117. 

Spoljašnje veze

• „Lysophospholipid Receptors: S₁P₅”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 08. 12. 2015. г. 
• Lysophospholipid+receptors на US National Library of Medicine Medical Subject Headings (MeSH)