RXFP4
| Relaksinu/insulinu-slična familija, peptidni receptor 4 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | RXFP4; GPCR142; GPR100; MGC126556; MGC126558; RLN3R2 | ||||||||||
| Vanjski ID | OMIM: 609043 MGI: 2182926 HomoloGene: 18775 IUPHAR: RXFP4 GeneCards: RXFP4 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 339403 | 242093 | |||||||||
| Ensembl | ENSG00000173080 | ENSMUSG00000049741 | |||||||||
| UniProt | Q8TDU9 | Q3B805 | |||||||||
| RefSeq (mRNA) | NM_181885 | NM_181817 | |||||||||
| RefSeq (protein) | NP_871001 | NP_861538 | |||||||||
| Lokacija (UCSC) |
Chr 1: 154.18 - 154.18 Mb |
Chr 3: 88.74 - 88.74 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
RXFP4, relaksinu/insulinu-slična familija, peptidni receptor 4, je humani G-protein spregnuti receptor.[1]
Ovaj receptor je ranije bio poznat pod nazivom GPR100.[1]
Vidi još[уреди | уреди извор]
Literatura[уреди | уреди извор]
Dodatna literatura[уреди | уреди извор]
- Bathgate RA; Ivell R; Sanborn BM; et al. (2005). „Receptors for relaxin family peptides.”. Ann. N. Y. Acad. Sci. 1041: 61—76. PMID 15956688. doi:10.1196/annals.1282.010.
- Bathgate RA; Ivell R; Sanborn BM; et al. (2006). „International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.”. Pharmacol. Rev. 58 (1): 7—31. PMID 16507880. doi:10.1124/pr.58.1.9.
- Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1-3): 97—101. PMID 12044878. doi:10.1016/S0014-5793(02)02775-8.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Liu C; Chen J; Sutton S; et al. (2004). „Identification of relaxin-3/INSL7 as a ligand for GPCR142.”. J. Biol. Chem. 278 (50): 50765—70. PMID 14522967. doi:10.1074/jbc.M308996200.
- Boels K, Schaller HC (2004). „Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor.”. Br. J. Pharmacol. 140 (5): 932—8. PMC 1574110 . PMID 14530218. doi:10.1038/sj.bjp.0705521.
- Fredriksson R; Höglund PJ; Gloriam DE; et al. (2003). „Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.”. FEBS Lett. 554 (3): 381—8. PMID 14623098. doi:10.1016/S0014-5793(03)01196-7.
- Liu C; Chen J; Kuei C; et al. (2005). „Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.”. Mol. Pharmacol. 67 (1): 231—40. PMID 15465925. doi:10.1124/mol.104.006700.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Liu C; Kuei C; Sutton S; et al. (2005). „INSL5 is a high affinity specific agonist for GPCR142 (GPR100).”. J. Biol. Chem. 280 (1): 292—300. PMID 15525639. doi:10.1074/jbc.M409916200.
- Gregory SG; Barlow KF; McLay KE; et al. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature. 441 (7091): 315—21. PMID 16710414. doi:10.1038/nature04727.
Spoljašnje veze[уреди | уреди извор]
- „Relaxin Family Peptide Receptors: RXFP4”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 03. 03. 2016. г.