Eksaprolol

С Википедије, слободне енциклопедије

Eksaprolol
Nazivi
IUPAC naziv
1-(2-Cikloheksilfenoksi)-3-(propan-2-ilamino)propan-2-ol
Drugi nazivi
Esprolol
Identifikacija
3D model (Jmol)
ChemSpider
KEGG[1]
UNII
  • CC(C)NCC(COC1=CC=CC=C1C2CCCCC2)O
Svojstva
C18H29NO2
Molarna masa 291,44 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Exaprolol je antagonist bet-adrenoreceptora.[4]

Sinteza[уреди | уреди извор]

Sinteza eksaprolola.[5]

Reference[уреди | уреди извор]

  1. ^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  2. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  3. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  4. ^ Van Waarde, A; Doorduin, J; De Jong, JR; Dierckx, RA; Elsinga, PH (2008). „Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET”. Neurochemistry International. 52 (4–5): 729—33. PMID 17961850. doi:10.1016/j.neuint.2007.09.009. 
  5. ^ Carissimi, M; Gentili, P; Grumelli, E; Milla, E; Picciola, G; Ravenna, F (1976). „Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol”. Arzneimittel-Forschung. 26 (4): 506—16. PMID 8056.