Indenolol

Indenolol
Nazivi
	IUPAC naziv 1-(1H-Inden-4-iloksi)-3-(propan-2-ilamino)propan-2-ol
Identifikacija
CAS broj	60607-68-3 ;
3D model (Jmol)	interaktivna slika;
ChemSpider	64962;
DrugBank	DB08952 ;
EC broj	262-323-5
KEGG	D08078;
PubChem C ID	71955;
UNII	3MZM7RWW00 ;
	SMILES CC(C)NCC(COC1=CC=CC2=C1C=CC2)O; ; ; ; ; ;
Svojstva
Hemijska formula	C15H21NO2
Molarna masa	247,34 g·mol−1
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	Reference infokutije

Indenolol je beta-adrenergijski blokator^[4] za lečenje hipertenzije (visokog krvnog pritiska). Istražen je tokom 1980-ih,^[5] ali prema podacima iz 2021. godine nije poznato da li će biti plasiran na tržište.^[6] On je derivat fenolnog 4-indenola.

Reference[уреди | уреди извор]

^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). „Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC”. Talanta. 78 (2): 458—63. PMID 19203609. doi:10.1016/j.talanta.2008.11.043.
^ Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). „Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol”. The Journal of Clinical Pharmacology. 25 (5): 328—336. PMID 4031109. S2CID 22844379. doi:10.1002/j.1552-4604.1985.tb02850.x.
^ ДругБанк DB08952. Accessed 2021-03-18.

[1] Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[2] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[3] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[4] Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). „Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC”. Talanta. 78 (2): 458—63. PMID 19203609. doi:10.1016/j.talanta.2008.11.043.

[5] Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). „Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol”. The Journal of Clinical Pharmacology. 25 (5): 328—336. PMID 4031109. S2CID 22844379. doi:10.1002/j.1552-4604.1985.tb02850.x.

[6] ДругБанк DB08952. Accessed 2021-03-18.

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