Metazosin

Metazosin
Nazivi
	IUPAC naziv 1-[4-(4-Amino-6,7-dimetoksihinazolin-2-il)piperazin-1-il]-2-metoksipropan-1-on
	Drugi nazivi Kenosin
Identifikacija
CAS broj	95549-92-1 ;
3D model (Jmol)	interaktivna slika;
ChemSpider	84417;
PubChem C ID	93514;
UNII	M3MC5CTU0R ;
	SMILES CC(C(=O)N1CCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC)OC; ; ; ; ; ;
Svojstva
Hemijska formula	C18H25N5O4
Molarna masa	375,43 g·mol−1
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	Reference infokutije

Metazosin je antihipertensivni antagonist α₁-adrenergičnog receptora.^[3]^[4]

Reference[уреди | уреди извор]

^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; Votavová, M; Remesová, J; Nezádalová, E (1990). „Pharmacology of a new antihypertensive agent, metazosin (Kenosin)”. Ceskoslovenska Farmacie. 39 (6): 266—74. PMID 1981860.
^ Lapka, R; Rejholec, V; Sechser, T; Peterková, M; Smíd, M (1989). „Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist”. Biopharmaceutics & Drug Disposition. 10 (6): 581—9. PMID 2575403. doi:10.1002/bdd.2510100607.