Amfepramon

Amfepramon
IUPAC ime
	2-(dietilamino)-1-fenilpropan-1-on
Klinički podaci
Prodajno ime	Adiposon, Amfepramon, Amfepramone, Amphepramon
Drugs.com	Monografija
Način primene	Oralno; Oralno;
Farmakokinetički podaci
Poluvreme eliminacije	4 do 6 sata.
Izlučivanje	Renalno
Identifikatori
CAS broj	134-80-5
ATC kod	A08AA03 (WHO)
PubChem	CID 7029
DrugBank	DB00937
ChemSpider	6762
KEGG	C06954
ChEMBL	CHEMBL4530
Hemijski podaci
Formula	C13H19NO
Molarna masa	205.2961
	SMILES CCN(CC)C(C)C(=O)C1=CC=CC=C1; ;
	InChI InChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3 ; Key:XXEPPPIWZFICOJ-UHFFFAOYSA-N ;

Amfepramon je depresant apetita. Smatra se da u manjoj meri uzrokuje poremećaje u centralnom nervnom sistemu od većine drugih lekova ove terapeutske kategorije. Takođe se smatra da je on među najbezbednijim lekovima za patijente sa hipertenzijom.^[1]^[2]^[3]^[4]^[5]

Reference[уреди | уреди извор]

^ AMA Drug Evaluations Annual, 1994, p2290
^ Adan RA, Vanderschuren LJ, la Fleur SE: Anti-obesity drugs and neural circuits of feeding. Trends Pharmacol Sci. 2008 Apr;29(4):208-17. Epub 2008 Mar 18. PMID 18353447
^ Arias HR, Santamaria A, Ali SF: Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion. Int Rev Neurobiol. 2009;88:223-55. PMID 19897080
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.
^ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.

Spoljašnje veze[уреди | уреди извор]

Amfepramone

Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).

[1] AMA Drug Evaluations Annual, 1994, p2290

[2] Adan RA, Vanderschuren LJ, la Fleur SE: Anti-obesity drugs and neural circuits of feeding. Trends Pharmacol Sci. 2008 Apr;29(4):208-17. Epub 2008 Mar 18. PMID 18353447

[3] Arias HR, Santamaria A, Ali SF: Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion. Int Rev Neurobiol. 2009;88:223-55. PMID 19897080

[4] Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.

[5] Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.

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