Brefonalol

Brefonalol
Nazivi
	IUPAC naziv 6-[1-Hidroksi-2-[(2-metil-4-fenilbutan-2-il)amino]etil]-3,4-dihidro-1H-hinolin-2-on
	Drugi nazivi Brefanolol
Identifikacija
CAS broj	104051-20-9 ;
3D model (Jmol)	interaktivna slika;
ChemSpider	59289;
PubChem C ID	65880;
UNII	DVO6SSG9S3 ;
	SMILES CC(C)(CCC1=CC=CC=C1)NCC(C2=CC3=C(C=C2)NC(=O)CC3)O; ; ; ; ; ;
Svojstva
Hemijska formula	C22H28N2O2
Molarna masa	352,48 g·mol−1
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	Reference infokutije

Brefonalol je beta-adrenargijaki antagonista koji smanjuje frekvenciju srca i krvni pritisak, i širi krvne sudove. On je proučavan oko 1990. godine,^[3] ali prema podacima iz 2021. godine nije poznato da će biti plasiran na tržište.

Reference[уреди | уреди извор]

^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Halabi, A; Endell, W; Halabi, I; Kirch, W (1990). „Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension”. Journal of Cardiovascular Pharmacology. 16 (1): 81—6. PMID 1696669. S2CID 41692901. doi:10.1097/00005344-199007000-00011 .

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[2] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[3] Halabi, A; Endell, W; Halabi, I; Kirch, W (1990). „Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension”. Journal of Cardiovascular Pharmacology. 16 (1): 81—6. PMID 1696669. S2CID 41692901. doi:10.1097/00005344-199007000-00011 .

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