(R)-3-Nitrobifenilin

(R)-3-Nitrobifenilin
IUPAC ime
	(R)-2-[1-(3'-Nitrobifenil-2-iloksi)etil]-4,5-dihidro-1H-imidazol
Klinički podaci
MedlinePlus	a682611
Identifikatori
ATC kod	none
PubChem	CID 16757089
ChemSpider	23288036
ChEMBL	CHEMBL242693
Hemijski podaci
Formula	C17H17N3O3
Molarna masa	311,334 g/mol
	SMILES c2ccc([N](=O)=O)cc2-c1ccccc1OC(C)C3=NCCN3; ;
	InChI InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1 ; Key:NMSAVNXFCXMJJY-GFCCVEGCSA-N ;

(R)-3-Nitrobifenilin je lek koji deluje kao α₂-adrenergički agonist. On je selektivan za α_2C tip receptora. On je isto tako slab antagonist na α_2A i α_2B tipovima.^[1]

Reference

^ Crassous PA, Cardinaletti C, Carrieri A, Bruni B, Di Vaira M, Gentili F, Ghelfi F, Giannella M, Paris H, Piergentili A, Quaglia W, Schaak S, Vesprini C, Pigini M (2007). „Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist”. Journal of Medicinal Chemistry. 50 (16): 3964—8. PMID 17630725. doi:10.1021/jm061487a.

Spoljašnje veze

[pmid17630725-1] Crassous PA, Cardinaletti C, Carrieri A, Bruni B, Di Vaira M, Gentili F, Ghelfi F, Giannella M, Paris H, Piergentili A, Quaglia W, Schaak S, Vesprini C, Pigini M (2007). „Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist”. Journal of Medicinal Chemistry. 50 (16): 3964—8. PMID 17630725. doi:10.1021/jm061487a.

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