Tolonidin

Из Википедије, слободне енциклопедије
Tolonidin
Tolonidine.png
Nazivi
IUPAC naziv
N-(2-hloro-4-metilfenil)-4,5-dihidro-1H-imidazol-2-amin
Identifikacija
3D model (Jmol)
KEGG[1]
Svojstva
C10H12ClN3
Molarna masa 209,67538
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
ДаY verifikuj (šta je ДаYНеН ?)
Reference infokutije

Tolonidin je antihipertenziv.[4][5][6]

Reference[уреди]

  1. Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  2. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  3. Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  4. Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). „Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate”. Arzneimittel-Forschung. 25 (10): 1557—1561. PMID 1243037. 
  5. Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). „Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis”. Arzneimittel-Forschung. 25 (11): 1802—1806. PMID 1243090. 
  6. Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). „Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity”. Arzneimittel-Forschung. 25 (12): 1926—1933. PMID 3186. 

Spoljašnje veze[уреди]