Benzofuranilpropilaminopentan

Benzofuranilpropilaminopentan
IUPAC ime
	(2R)-1-(1-Benzofuran-2-il)-N-propilpentan-2-amin
Identifikatori
CAS broj	260550-89-8
ATC kod	None
PubChem	CID 9859674
ChemSpider	7992053
Hemijski podaci
Formula	C16H23NO
Molarna masa	245,37
	SMILES CCC[C@@H](NCCC)CC1=CC2=C(C=CC=C2)O1; ;
	InChI InChI=1S/C16H23NO/c1-3-7-14(17-10-4-2)12-15-11-13-8-5-6-9-16(13)18-15/h5-6,8-9,11,14,17H,3-4,7,10,12H2,1-2H3/t14-/m1/s1 ; Key:LJHIBIVAYHQPBT-CQSZACIVSA-N ;

(-)-1-(Benzofuran-2-il)-2-propilaminopentan ((-)-BPAP)^[1] je lek sa neobičnim profilom dejstva. On se u izvesnoj meri može grupisanti u familje stimulanata i antidepresiva, mada je njegov mehanizam dejstva veoma različit.^[2]^[3]

Reference

^ US Patent 6214859
^ Shimazu S, Takahata K, Katsuki H, Tsunekawa H, Tanigawa A, Yoneda F, Knoll J, Akaike A. (-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release. Shimazu, Seiichiro; Takahata, Kazue; Katsuki, Hiroshi; Tsunekawa, Hiroko; Tanigawa, Akie; Yoneda, Fumio; Knoll, Joseph; Akaike, Akinori (2001). „(−)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release”. European Journal of Pharmacology. 421 (3): 181—189. PMID 11516435. doi:10.1016/S0014-2999(01)01040-8. .
^ Shimazu S, Tsunekawa H, Yoneda F, Katsuki H, Akaike A, Janowsky A. Transporter Mediated Actions of R-(-)-1-(Benzofuran-2-yl)-2-propylaminopentane. Shimazu, Seiichiro; Tsunekawa, Hiroko; Yoneda, Fumio; Katsuki, Hiroshi; Akaike, Akinori; Janowsky, Aaron (2003). „Transporter-mediated actions of R-(−)-1-(benzofuran-2-yl)-2-propylaminopentane”. European Journal of Pharmacology. 482 (1–3): 9—16. PMID 14659999. doi:10.1016/j.ejphar.2003.09.044. .

Spoljašnje veze

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[1] US Patent 6214859

[2] Shimazu S, Takahata K, Katsuki H, Tsunekawa H, Tanigawa A, Yoneda F, Knoll J, Akaike A. (-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release. Shimazu, Seiichiro; Takahata, Kazue; Katsuki, Hiroshi; Tsunekawa, Hiroko; Tanigawa, Akie; Yoneda, Fumio; Knoll, Joseph; Akaike, Akinori (2001). „(−)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release”. European Journal of Pharmacology. 421 (3): 181—189. PMID 11516435. doi:10.1016/S0014-2999(01)01040-8. .

[3] Shimazu S, Tsunekawa H, Yoneda F, Katsuki H, Akaike A, Janowsky A. Transporter Mediated Actions of R-(-)-1-(Benzofuran-2-yl)-2-propylaminopentane. Shimazu, Seiichiro; Tsunekawa, Hiroko; Yoneda, Fumio; Katsuki, Hiroshi; Akaike, Akinori; Janowsky, Aaron (2003). „Transporter-mediated actions of R-(−)-1-(benzofuran-2-yl)-2-propylaminopentane”. European Journal of Pharmacology. 482 (1–3): 9—16. PMID 14659999. doi:10.1016/j.ejphar.2003.09.044. .

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